British Air Force Typhoon FGR4s have operated alongside French warplanes in a joint strike on an hidden munitions depot in Syria employed by the IS group, per a report from the UK's MoD.
The site, located using intelligence, was assessed as storing arms and explosives, the statement said, and was situated in mountains just above the historic site of Palmyra in central Syria.
"Our fighter planes used laser-guided Paveway IV weapons to target a several entry passages leading to the facility... initial indications indicate the objective was successfully hit," the MoD said.
There was no sign of any harm to civilians in the attack conducted Saturday night and all the aircraft returned to base without incident, the ministry further stated.
The Typhoon FGR4s were assisted by a Voyager refuelling tanker.
IS - also known as ISIS - enforced extremist governance over parts of both Syria and Iraq before its territorial defeat in 2019.
"This strike demonstrates British leadership, and determination to stand shoulder to shoulder with allied nations, to eliminate any re-emergence of Daesh and their harmful and extremist ideologies in the region," Britain's Defence Chief John Healey remarked.
British military aircraft have performed patrols over Syrian airspace to "forestall any attempted comeback" of the group subsequent to its routing at the Baghuz confrontation in 2019, the authorities noted.
"I must thank every member of British forces who took part in this operation for their skill and their courage," the Defence Secretary commented. "They were part of numerous British personnel stationed over Christmas and New Year. This mission, to remove militants who pose a risk to our security, demonstrates how British military are always on standby, throughout the year, ensuring Britain's security within its borders and powerful internationally."
In December, the United States armed forces executed what it termed a "major assault" on Islamic State objectives in the country, following an ambush resulted in the deaths of two US troops and a civilian interpreter in Palmyra.
The United Nations estimates IS still has roughly 5-7 thousand fighters in Iraq and Syria.